Montelukast is a prescription medication used to treat the symptoms of asthma and itchy, stuffy, or runny nose caused by allergies.It is also used to prevent …

No deaths occurred following a single oral administration of montelukast sodium at doses up to 5,000 mg/kg in mice and rats (15,000 mg/m2 and 30,000 mg/m2 in mice and rats, respectively), the maximum dose tested. This dose is equivalent to 25,000 times the recommended daily adult human dose (based on an adult patient weight of 50 kg).

Biodegradation inoculum source screening", Toxikon. Environmental Sciences, 22 April 1996. Toxikon Corporation, 1996. screening", Toxikon Environmental Sciences, 22 April 1996. Toxikon Corporation, 1996. "Montelukast Sodium (MK0746): Determination of the Rate of Hydrolysis.

Montelukast sodium

使用本药至少6个月，253名患者用药一年，21名用药达2年，长期用药的不良反应情况与上述无异。中文名: 孟鲁司特钠; 外文名: Montelukast Sodium Tablets. View and buy high purity Montelukast sodium. CysLT1 and GPR17 antagonist. Cited in 1 publication. 10 May 2019 Clinical efficacy of montelukast sodium combined with budesonide or combined with loratadine in treating children with cough variant asthma Clinical effect of montelukast sodium combined with inhaled corticosteroids in the treatment of OSAS children. Yang, Da-Zhi MD; Liang, Jia MD; Zhang, Feng MD Each tablet contains: Montelukast (as sodium) 10 mg.

Montelukast sodium | C35H35ClNNaO3S | CID 23663996 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

It can also be used to prevent 中文品名, 欣流口服顆粒劑, 藥品圖形檔, 藥品圖示. 商品名, Singulair Oral Granules 4mg. 學名, Montelukast sodium.

Montelukast sodium Form B may be used for the preparation of topical compositions such as in transdermal devices, aerosols, creams, ointments, lotions, dusting powders, nasal spray and the like in accordance with conventional pharmaceutical formulation practices well known in the art.

Översättnings-API; Om MyMemory; Logga in SINGULAIR® (montelukast sodium) tablets, for oral use SINGULAIR® (montelukast sodium) chewable tablets, for oral use SINGULAIR® (montelukast sodium) oral granules Initial U.S. Approval:1998 WARNING: SERIOUS NEUROPSYCHIATRIC EVENTS See full prescribing information for complete boxed warning. Montelukast Sodium sc-202231 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Montelukast Sodium STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA SUPPLIER Santa Cruz Biotechnology, Inc. 2145 Delaware Avenue Santa Cruz Montelukast Sodium(Singulair) is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affect on the CysLT2 receptor.

Montelukast sodium is the active pharmaceutical ingredient of SINGULAIR®, and is approved for the treatment of asthma and allergic rhinitis. The molecular structure of montelukast is as shown below: Montelukast sodium is described in U.S. Pat. No. 5,565,473. Montelukast is a leukotriene receptor antagonist that demonstrates a marked affinity and selectivity to the cysteinyl leukotriene receptor type-1 in preference to many other crucial airway receptors like the prostanoid, cholinergic, or beta-adrenergic receptors.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] As a consequence, the agent can elicit substantial blockage of LTD4 leukotriene-mediated مونتيلوكاست صوديوم (بالإنجليزية: Montelukast sodium)‏ هو عقار دوائي مخصص للوقاية وللعلاج المزمن بمرض الربو لدى البالغين والاطفال من سن سنتين وأكثر. Montelukast (sodium salt) SAFETY DATA SHEET Supersedes Revision: 02/24/2014 according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008 1.1 Product Code: 10008318 Section 1. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Montelukast (sodium salt) Company Name: Cayman Chemical Company montelukast sodium could not be determined in this age group. Geriatrics (>65 years of age): In clinical studies, there were no age-related differences in the efficacy or safety profiles of montelukast sodium. Effects on Ability to Drive and Use Machines There is no evidence that montelukast sodium affects the ability to drive and use machines.
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It is generally less preferred for this use than inhaled corticosteroids. It is not useful for acute asthma attacks. Other uses include allergic rhinitis and hives of long duration.

Se hela listan på rxlist.com Se hela listan på medbroadcast.com Search results for Montelukast Sodium at Sigma-Aldrich.
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Montelukast is clinically used to treat allergic rhinitis and asthma, although it also attenuates cough and decreases eosinophil infiltration. Montelukast decreases expression of p38 MAPK, NF-κB, IL-1β, IL-6, and TNF-α and inhibits activation of microglia, attenuating neuropathic pain in animal models of chronic constrictive injury (CCI).

Common side effects include abdominal pain, cough 2020-10-24 · Uses of Montelukast Tablets: It is used to ease allergy signs. It is used to prevent breathing problems that happen with exercise. It is used to treat or prevent asthma. Montelukast Sandoz används för behandling av vuxna och ungdomar, 15 år och äldre som inte fått fullgod kontroll med tidigare astmamedicinering och därför behöver tilläggsbehandling. Montelukast Sandoz förebygger också sammandragning av luftvägarna i samband med fysisk ansträngning. Montelukast sodium is a hygroscopic, optically active, white to off-white powder.

av E Shebani · 2006 · Citerat av 9 — montelukast caused apoptosis and necrosis of airway epithelial cells, traperitoneally by sodium pentobarbital injection, and were dissected

Empirical Formula (Hill Notation): C 35 H 35 ClNO 3 S·Na. Molecular Weight: 608.17. You have selected the … Montelukast sodium is a hygroscopic, optically active, white to off-white powder. Montelukast sodium is freely soluble in ethanol, methanol, and water and practically insoluble in acetonitrile. 2021-02-17 P/200/2009: European Medicines Agency decision of 1 October 2009 on the acceptance of a modification of an agreed Paediatric Investigation Plan for montelukast sodium (Singulair), (EMEA-000012-PIP01-07-M01) in accordance Montelukast Sandoz används för behandling av vuxna och ungdomar, 15 år och äldre som inte fått fullgod kontroll med tidigare astmamedicinering och därför behöver tilläggsbehandling.

Montelukast (sodium salt) SAFETY DATA SHEET Supersedes Revision: 02/24/2014 according to Regulation (EC) No. 1907/2006 as amended by (EC) No. 1272/2008 1.1 Product Code: 10008318 Section 1. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Montelukast (sodium salt) Company Name: Cayman Chemical Company montelukast sodium could not be determined in this age group. Geriatrics (>65 years of age): In clinical studies, there were no age-related differences in the efficacy or safety profiles of montelukast sodium.